GENERAL CATALOGUE
Prothionamide
HY-B0306 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B0306
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Catalog No: HY-B0306
CAS No: 14222-60-7
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 ?M. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis MIC = 0.5 AAasAasAAmug/mL and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy.
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