Prothrombin Mutant (R393Q) Stable Expressing HEK293 Cell Line

Description

Mannan-binding lectin-associated serine protease-1 MASP-1 is a protein of the lectin pathway. Its similar in terms of structural features and substrate specificity to thrombin. Via its ability to induce fibrin clot formation along with interplay with several coagulation factors, MASP-1 has been shown to activate prothrombin. With the Prothrombin Mutant R393Q Stable Expressing HEK293 Cell Line, you can investigate in detail the mechanism of MASP-1 in mediating prothrombin activation.