GENERAL CATALOGUE
Prucalopride
HY-14151 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-14151
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Catalog No: HY-14151
CAS No: 179474-81-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist high affinity , with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer.
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