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Prucalopride hydrochloride
GENERAL CATALOGUE

Prucalopride hydrochloride

HY-14152 · 50 mg

MedChemExpress · Cat: HY-14152

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Catalog No: HY-14152
CAS No: 179474-80-7
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress

Description

Prucalopride hydrochloride is an orally active, selective and specific 5-HT4 receptor agonist high affinity , with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride hydrochloride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride hydrochloride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride hydrochloride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer.

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