GENERAL CATALOGUE
Prucalopride succinate
HY-12694 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-12694
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medchemexpress.com/Prucalopride-succinate.htmlCatalog No: HY-12694
CAS No: 179474-85-2
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Prucalopride succinate is an orally active, selective and specific 5-HT 4 receptor agonist high affinity , with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride succinate improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride succinate also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride succinate can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer.
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