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PSB-24000
GENERAL CATALOGUE

PSB-24000

HY-172801 · 50 mg

MedChemExpress · Cat: HY-172801

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medchemexpress.com/psb-24000.html
Catalog No: HY-172801
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

PSB-24000 Compound 27 is a selective ecto-5-nucleotidase CD73 inhibitor with a Ki value of 563 nM against human CD73 Ki= 481 nM at membrane-bound CD73 in triple-negative breast cancer cells . PSB-24000 interferes with CD73s recognition and action on the substrate AMP, and prevents the generation of immunosuppressive and cancer-promoting adenosine from AMP. PSB-24000 is promising for research of cancers.

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