PSMA targeting peptide

Description

PSMA-1 is a PSMA targeting peptide GRFLTGGTGRLLRIS and can be used for for targeted delivery of glucose-regulated protein GRP -silencing siRNAs in PCa cells. PSMA-1 is selected and polyarginine sequences R6 or R9 were added at the C terminus to generate the CTPs. FITC labeling of the peptide with an aminohexanoic acid Ahx linker at the N terminus produced FITC-PSMA-1?to track PSMA binding on PCa cells.