GENERAL CATALOGUE
PT-262
HY-100035 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100035
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Catalog No: HY-100035
CAS No: 86811-36-1
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 ?M. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent pathway. PT-262 blocks cytoskeleton function and cell migration. PT-262 has anti-cancer activity.
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