GENERAL CATALOGUE
PT4
HY-146166 · 50 mg
MedChemExpress · Cat: HY-146166
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Catalog No: HY-146166
CAS No: 1280738-47-7
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
PT4 is a therapeutic agent against Cutaneous leishmaniasis CL . PT4 is effective against both species of Leishmania, with IC50s of 125.18 and 233.18 ?M for L. amazonensis and L. braziliensis, respectively. PT4 decreases of mitochondrial membrane potential and increases production of reactive oxygen species, which leads to parasite death. PT4 has a potent in vivo anti-inflammatory activity.
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