PTEN (human), (recombinant) (His-tag)

Description

PTEN phosphatase and tensin homologue deleted on chromosome 10, MMAC is a lipid phosphatase which can also act as a tyrosine, serine and threonine protein phosphatase. It is specific for acidic substrates such as phosphatidylinositol 3,4,5 -trisphosphate, which is its main biological substrate that mediates growth factor-induced activation of intracellular signalling through the serine-threonine kinase Akt