Pumilio 1 Antibody, mAb, Rabbit

Description

Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element PRE , 5-UGUANAUA-3, that is related to the Nanos Response Element NRE .Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation.