Punicic acid

Description

Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated ?-linolenic acid and ?-5 polyunsaturated fatty acids. Punicic acid has anti-inflammatory and antioxidant activities and can inhibit the expression of inflammatory mediators such as tumor necrosis factor ? TNF-? . Punicic acid can also reduce the formation of ?-amyloid deposits and hyperphosphorylation of tau by increasing the expression of GLUT4 protein and inhibiting the overactivation of calpain, and is used to prevent and treat neurodegenerative diseases. In addition, punicic acid also has breast cancer inhibitor properties that depend on lipid peroxidation and PKC pathways.