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PV1162
GENERAL CATALOGUE

PV1162

HY-164523 · 50 mg

MedChemExpress · Cat: HY-164523

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medchemexpress.com/pv1162.html
Catalog No: HY-164523
CAS No: 1346559-65-6
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

PV1162 is a selective Chk2 inhibitor with an IC50 of 0.29 nM. PV1162 inhibits ATP binding to Chk2 by targeting the gatekeeper-dependent hydrophobic pocket, which is specific to Chk2 and located behind the ATP-binding site adenine-binding region , thereby inhibiting the phosphorylation activity of Chk2. PV1162 holds potential application value in the field of cancer therapy.

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