

HY-14435 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-14435
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Manufacturer product page
medchemexpress.com/Pyridone-6.html
Description
Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities 130 nM to 10 mM for other protein tyrosine kinases.

