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Pyridostatin hydrochloride
GENERAL CATALOGUE

Pyridostatin hydrochloride

HY-15176A · 10 mM * 1 mL in Water

MedChemExpress · Cat: HY-15176A

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Catalog No: HY-15176A
CAS No: 1781882-65-2
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress

Description

Pyridostatin RR82 hydrochloride is a G-quadruplex DNA stabilizing agent Kd=490 nM and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells.

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