GENERAL CATALOGUE
Pyrrothiogatain
HY-138113 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-138113
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Catalog No: HY-138113
CAS No: 477888-48-5
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Pyrrothiogatain is a transcription factor GATA3 inhibitor with an IC50 of 54.7 ?M. Pyrrothiogatain inhibits the DNA-binding activity of GATA3 and inhibits the T helper 2 Th2 cell differentiation and expression of Th2 cytokines. Pyrrothiogatain shows anti-infection effect by inhibiting ACE2 expression. Pyrrothiogatain can be used for the researches of inflammation, immunology, infection and cancer, such as colon cancer and SARS-CoV-2 infection.
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