GENERAL CATALOGUE
PZ-2891
HY-124634 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-124634
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Manufacturer product page
medchemexpress.com/PZ-2891.htmlCatalog No: HY-124634
CAS No: 2170608-82-7
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase PANK modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1?, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively.
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