GENERAL CATALOGUE
Q94 hydrochloride
HY-108554 · 50 mg
MedChemExpress · Cat: HY-108554
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medchemexpress.com/q94-hydrochloride.htmlCatalog No: HY-108554
CAS No: 1052076-77-3
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
Q94 hydrochloride, a selective PAR1 antagonist IC50=916 nM , can selectively block PAR1/G?q interaction and signalling. Q94 hydrochloride blocks PAR1-mediated increases in both CCL2 mRNA and protein levels in a dose-dependent manner. Q94 hydrochloride also completely blocks thrombin-induced ERK1/2 and MLC phosphorylation.
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