GENERAL CATALOGUE
Quiflapon
HY-10037 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10037
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Catalog No: HY-10037
CAS No: 136668-42-3
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Quiflapon MK-591 is a selective and specific 5-lipoxygenase-activating protein FLAP inhibitor with an IC50 of 1.6 nM in a FLAP binding assay. Quiflapon is also a potent and orally active Leukotriene biosynthesis LT inhibitor, shows IC50 values of 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively. Quiflapon induces cell apoptosis.
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