GENERAL CATALOGUE
Quizartinib-d8
HY-13001S · 50 mg
MedChemExpress · Cat: HY-13001S
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/quizartinib-d8.html
Sponsored
Catalog No: HY-13001S
CAS No: 1300734-19-3
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Quizartinib-d8 AC220-d8 is deuterium labeled Quizartinib. Quizartinib AC220 is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a Kd of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC50s of 4.2 and 1.1 nM, respectively. Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib induces apoptosis.
More from MedChemExpress
2-Bromohexadecanoic acid
HY-111770
Apoptosis
Uridine 5'-monophosphate-15N2
HY-101981S
Apoptosis
AZD-5991
HY-101533
Apoptosis
HDAC-IN-37
HY-146750
Apoptosis
Anti-inflammatory agent 47
HY-155568
Apoptosis
YLT205
HY-117515
Apoptosis
pan-HER-IN-2
HY-144677
Apoptosis
HDAC-IN-84
HY-170379
Apoptosis