Quorum sensing-IN-9

Name: Quorum sensing-IN-9
Brand: MedChemExpress

HY-168948 · 50 mg

MedChemExpress · Cat: HY-168948

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medchemexpress.com/quorum-sensing-in-9.html

Catalog No: HY-168948

CAS No: 3063543-24-5

Category: Anti-infection

Pack Size: 50 mg

Brand: MedChemExpress

Description

Quorum sensing-IN-9 Compound 7d inhibits quorum sensing in Pseudomonas aeruginosa by binding PqsR proteins. Quorum sensing-IN-9 inhibits the expression of quorum sensing systems related genes lasB, rhlA and pqsA, blocks the generation of virulence factors elastase, pyocyanin and rhamnolipid. Quorum sensing-IN-9 destorys the motility of P. aeruginosa, inhibits the biofilm formation, decreasing the virulence and pathogenicity of P. aeruginosa. Quorum sensing-IN-9 exhibits anti-infectious activity in Galleria mellonella larval model.