(R)-Bambuterol

Description

R -Bambuterol is a ?2-receptor agonist with anti-asthmatic and colitis-improving activity. R -Bambuterol is indicated for the treatment of asthma and chronic obstructive pulmonary disease and has the advantage of a once-daily dosing and a favorable side effect profile. R -Bambuterol significantly reduced disease severity in a mouse model of colitis, more effectively than RS -Bambuterol or S -Bambuterol. R -Bambuterol can significantly reduce the levels of inflammatory cytokines and reduce the infiltration of macrophages in mice with colitis. R -Bambuterol also increases ?2-adrenoceptor levels and reduces the expression of IL-6, IL-17 and other related proteins in colon tissue in a dose-dependent manner.