GENERAL CATALOGUE
(R)-SR-C-107
HY-169937 · 50 mg
MedChemExpress · Cat: HY-169937
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Manufacturer product page
medchemexpress.com/r-sr-c-107.htmlCatalog No: HY-169937
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
R -SR-C-107 is an orally available inhibitor of ENL YEAST domain-containing protein designed to target acute myeloid leukemia AML . R -SR-C-107 targets ENL with IC50 and KD of 40 nM and 144 nM, respectively. R -SR-C-107 demonstrates in vivo efficacy in a xenograft mouse model of AML, with a tumor regression rate of 45 % at a dose of 200 mg/kg PO; QD .
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