GENERAL CATALOGUE
R406 free base
HY-11108 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-11108
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Catalog No: HY-11108
CAS No: 841290-80-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation. R406 free base also inhibits Lyn IC50=63 nM and Lck IC50=37 nM .
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