GENERAL CATALOGUE
R406
HY-12067 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-12067
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medchemexpress.com/R406.htmlCatalog No: HY-12067
CAS No: 841290-81-1
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 reduces immune complex-mediated inflammation. R406 also inhibits Lyn IC50=63 nM and Lck IC50=37 nM .
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