GENERAL CATALOGUE
RA-9
HY-136528 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-136528
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Catalog No: HY-136528
CAS No: 919091-63-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
RA-9 is a potent and selective proteasome-associated deubiquitinating enzymes DUBs inhibitor with favorable toxicity profile and anticancer activity. RA-9 blocks ubiquitin-dependent protein degradation without impacting 20S proteasome proteolytic activity. RA-9 selectively induces onset of apoptosis in ovarian cancer cell lines and primary cultures derived from donors. RA-9 induces endoplasmic reticulum ER -stress responses in ovarian cancer cells.
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