Racemomycin B

Description

Racemomycin B 229-B; Streptothricin D , the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three ?-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration MIC of 0.4 ?g/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 ?g/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of ?-lysine groups.