Rad9 Mouse Monoclonal Antibody

Description

EnkiLife offers the Rad9 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Monkey species and is suitable for WB,IP application. Alternative Names of Immunogen: RAD9; hRAD9. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IP 1:20-1:50 Background: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Research Area: Epigenetics and Nuclear Signaling