GENERAL CATALOGUE
Raloxifene 6-glucuronide-d4 lithium
HY-135581S1 · 1 mg
MedChemExpress · Cat: HY-135581S1
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Catalog No: HY-135581S1
Pack Size: 1 mg
Brand: MedChemExpress
Description
Raloxifene 6-glucuronide-d4 lithium is deuterium labeled Raloxifene 6-glucuronide. Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 ?M. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGF?3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression.
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