RAP80 Rabbit Monoclonal Antibody

Description

EnkiLife offers the RAP80 Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC/IF application. Alternative Names of Immunogen: RAP80; X2HRIP110. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200 Background: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Research Area: Epigenetics and Nuclear Signaling