

HY-N15826 · 50 mg
MedChemExpress · Cat: HY-N15826
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medchemexpress.com/rbm1-151.htmlDescription
RBM1-151, a 1-deoxy derivative and vinilog of RBM14-C12 HY-150163 , as a fluorogenic substrate of Amidases HY-P2736 Ex/Em . RBM1-151 is hydrolyzed by acid ceramidase AC appKm = 7.0 ?M; appVmax = 99.3 nM/min , N-acylethanolamine-hydrolyzing acid amidase appKm = 0.73 ?M; appVmax = 0.24 nM/min , and fatty Acid amide hydrolase FAAH appKm = 3.6 ?M; appVmax = 7.6 nM/min but not by other ceramidases. RBM1-151 is applicable for basic biological studies of lipid amidase function, as well as potential diagnostic/prognostic evaluations of diseases involving dysregulated AC, NAAA, or FAAH Farber disease, cancer .







