GENERAL CATALOGUE
RBN012759
HY-136979 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-136979
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medchemexpress.com/rbn012759.htmlCatalog No: HY-136979
CAS No: 2360851-29-0
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
RBN012759 is a potent, selective and orally active inhibitor of PARP14, with an IC50 of <3 nM. RBN012759 displays 300-fold selectivity over the monoPARPs and 1000-fold selectivity over the polyPARPs. RBN012759 decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.
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