GENERAL CATALOGUE
RBN013209
HY-144987 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-144987
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Catalog No: HY-144987
CAS No: 2597933-17-8
Category: Immunology Inflammation
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
RBN013209 is an orally active small molecule inhibitor of CD38 with an IC50 of 0.01 to 0.1 ?M for human CD38. RBN013209 prevents the conversion of extracellular NAD+ to ADPR or cADPR in tumor cells and PBMCs. RBN013209 can be used in the study of tumor. In addition, RBN013209 enables CAR-T cells to maintain the naive state and central memory state, and decreases the expression of cell activation markers and exhaustion-related inhibitory receptors.
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