GENERAL CATALOGUE
RD-23
HY-168867 · 50 mg
MedChemExpress · Cat: HY-168867
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medchemexpress.com/rd-23.html
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Catalog No: HY-168867
CAS No: 3053537-06-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
RD-23 is an orally active and selective RET PROTAC degrader. RD-23 promotes ubiquitination and degradation of RETG810C mutation, with a DC50 value of 11.7 nM. RD-23 inhibits the activation of downstream Shc signaling and induces Apoptosis. RD-23 can be used for the research of RET-related cancers Pink: RET ligand-2 HY-168868 ; Blue: E3 ligase CRBN ligand; Black: linker .
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