

HY-170649 · 50 mg
MedChemExpress · Cat: HY-170649
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medchemexpress.com/rdrp-in-9.htmlDescription
RdRP-IN-9 Compound 6b is a reversible covalent allosteric inhibitor of RdRp. RdRP-IN-9 demonstrates high anti-coronavirus activity, with an EC50 value of 0.68 ?M against HCoV-OC43 RdRP-IN-9 exerts a more prolonged antiviral effect by reversibly acylating Cys12 in the NiRAN domain of non-structural protein 12 nsp 12 and exhibits synergistic anti-coronavirus activity with Molnupiravir HY-135853 .







