Recombinant Cynomolgus CD73 (C-6His)

Description

EnkiLife provides the Recombinant Cynomolgus CD73 (C-6His) protein,aslo know as 5-Nucleotidase,5-NT,Ecto-5-Nucleotidase,CD73,NT5E,NT5,NTE, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Cynomolgus 5-nucleotidase/CD73 is produced by our Mammalian expression system and the target gene encoding Trp27-Lys547 is expressed with a 6His tag at the C-terminus.Accession:G7P3J1. Expression Host:Human Cells.Species:Cynomolgus.Predicted Molecular Mass:58.8 KDa. Background:CD73, also known as Ecto-5-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.