Recombinant Human 4-1BB (C-mFc)

Description

EnkiLife provides the Recombinant Human 4-1BB (C-mFc) protein,aslo know as CD137,ILA,TNFRSF9,4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human 4-1BB Ligand Receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a mouse IgG1 Fc tag at the C-terminus.Accession:Q07011. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:43.9 KDa. Background:Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.