Recombinant Human AIF1 (C-6His)

Description

EnkiLife provides the Recombinant Human AIF1 (C-6His) protein,aslo know as Allograft Inflammatory Factor 1,AIF-1,Ionized Calcium-Binding Adapter Molecule 1,Protein G1,AIF1,G1,IBA1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Allograft Inflammatory Factor 1 is produced by our E.coli expression system and the target gene encoding Ser2-Pro147 is expressed with a 6His tag at the C-terminus.Accession:P55008. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:17.7 KDa. Background:Allograft Inflammatory Factor 1 (AIF1) contains two EF-hand domains and exists as a homodimer. AIF1 can be detected in T-lymphocytes and peripheral blood mononuclear cells. AIF1 functions as actin-binding protein that enhances membrane ruffling and RAC activation and can enhance the actin-bundling activity of LCP1. In addition, AIF1 plays a role in RAC signaling and in phagocytosis and may also in macrophage activation and function. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes and plays a role in vascular inflammation.