Recombinant Human ALDH1A1 (N-6His)

Description

EnkiLife provides the Recombinant Human ALDH1A1 (N-6His) protein,aslo know as Retinal Dehydrogenase 1,RALDH 1,RalDH1,ALDH-E1,ALHDII,Aldehyde Dehydrogenase Family 1 Member A1,Aldehyde Dehydrogenase Cytosolic,ALDH1A1,ALDC,ALDH1,PUMB1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Aldehyde Dehydrogenase Family 1 Member A1 is produced by our E.coli expression system and the target gene encoding Met1-Ser501 is expressed with a 6His tag at the N-terminus.Accession:P00352. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:57 KDa. Background:Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.