Recombinant Human ALDH1A3 (N-6His)

Description

EnkiLife provides the Recombinant Human ALDH1A3 (N-6His) protein,aslo know as Aldehyde dehydrogenase family 1 member A3,ALDH1A3,Aldehyde dehydrogenase 6,Retinaldehyde dehydrogenase 3,RALDH-3,ALDH6, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Aldehyde Dehydrogenase Family 1 Member A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus.Accession:P47895. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:57.5 KDa. Background:Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.