Recombinant Human ALK-1 (C-Fc)

Description

EnkiLife provides the Recombinant Human ALK-1 (C-Fc) protein,aslo know as Serine/Threonine-Protein Kinase Receptor R3,SKR3,Activin Receptor-Like Kinase 1,ALK-1,TGF-B Superfamily Receptor Type I,TSR-I,ACVRL1,ACVRLK1,ALK1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Activin Receptor-Like Kinase 1 is produced by our Mammalian expression system and the target gene encoding Asp22-Gln118 is expressed with a human IgG1 Fc tag at the C-terminus.Accession:P37023. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:37.6 KDa. Background:Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair.