Recombinant Human AMIGO2 (C-6His)

Description

EnkiLife provides the Recombinant Human AMIGO2 (C-6His) protein,aslo know as Amphoterin-Induced Protein 2,AMIGO-2,Alivin-1,Differentially Expressed in Gastric Adenocarcinomas,DEGA,AMIGO2,ALI1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Amphoterin-induced Gene And ORF 2 is produced by our Mammalian expression system and the target gene encoding Gly40-His393 is expressed with a 6His tag at the C-terminus.Accession:Q86SJ2. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:41.34 KDa. Background:Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.