Recombinant Human ANG1 (N-Fc)

Description

EnkiLife provides the Recombinant Human ANG1 (N-Fc) protein,aslo know as AGP1,AGPT,Ang1,ANG-1,angiopoietin 1,Angiopoietin-1,ANGPT1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Angiopoietin-1 is produced by our Mammalian expression system and the target gene encoding Asp256-Phe498 is expressed with a human IgG1 Fc tag at the N-terminus.Accession:Q15389. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:53.9 KDa. Background:Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.