Recombinant Human APBA3 (C-6His)

Description

EnkiLife provides the Recombinant Human APBA3 (C-6His) protein,aslo know as Amyloid Beta A4 Precursor Protein-Binding Family A Member 3,Adapter protein X11Gamma,Neuron-Specific X11L2 Protein,Neuronal Munc18-1-Interacting Protein 3,Mint-3,APBA3,MINT3,X11L2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Amyloid Beta A4 Precursor Protein-Binding Family A Member 3 is produced by our E.coli expression system and the target gene encoding Met1-Leu138 is expressed with a 6His tag at the C-terminus.Accession:O96018. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:15.48 KDa. Background:Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimers disease amyloid precursor protein. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.