Recombinant Human APLP-1 (C-6His)

Description

EnkiLife provides the Recombinant Human APLP-1 (C-6His) protein,aslo know as Amyloid-like protein 1,APLP,APLP-1,C30,APLP1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Amyloid-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Gly42-Pro212 is expressed with a 6His tag at the C-terminus.Accession:P51693. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:19.8 KDa. Background:Amyloid-like protein 1 (APLP-1) is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development, and is genetically linked to Alzheimersdisease.