Recombinant Human ARSA (C-6His)

Description

EnkiLife provides the Recombinant Human ARSA (C-6His) protein,aslo know as Arylsulfatase A,ASA,Cerebroside-Sulfatase,ARSA, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus.Accession:AAH14210.2. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:52.9 KDa. Background:Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.