Recombinant Human ASF1A (C-6His, N-T7 tag)

Description

EnkiLife provides the Recombinant Human ASF1A (C-6His, N-T7 tag) protein,aslo know as Histone Chaperone ASF1A,Anti-Silencing Function Protein 1 Homolog A,hAsf1,hAsf1a,CCG1-Interacting Factor A,CIA,hCIA,ASF1A, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Histone Chaperone ASF1A is produced by our E.coli expression system and the target gene encoding Met1-Met204 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.Accession:Q9Y294. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:25.4 KDa. Background:Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.