Recombinant Human ASGPR1 (C-6His)

Description

EnkiLife provides the Recombinant Human ASGPR1 (C-6His) protein,aslo know as Asialoglycoprotein Receptor 1,ASGP-R 1,ASGPR 1,C-Type Lectin Domain Family 4 Member H1,Hepatic Lectin H1,HL-1,ASGR1,CLEC4H1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Asialoglycoprotein Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln62-Ile291 is expressed with a 6His tag at the C-terminus.Accession:P07306. Expression Host:Human Cells.Species:Human.Predicted Molecular Mass:27.43 KDa. Background:Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor, belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits, ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins, recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1, results in the complex is internalized and transported to a sorting organelle, then ASGPR1 and ligand can be disassociated, ASGPR1 returns to the cell membrane surface.