Recombinant Human ATG3

Description

EnkiLife provides the Recombinant Human ATG3 protein,aslo know as Ubiquitin-like-conjugating enzyme ATG3,Autophagy-related protein 3,APG3-like,hApg3,Protein PC3-96,ATG3,APG3,APG3L, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed.Accession:Q9NT62. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:36 KDa. Background:Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.