Recombinant Human ATG4A (N-6His)

Description

EnkiLife provides the Recombinant Human ATG4A (N-6His) protein,aslo know as Cysteine Protease ATG4A,AUT-Like 2 Cysteine Endopeptidase,Autophagin-2,Autophagy-Related Cysteine Endopeptidase 2,Autophagy-Related Protein 4 Homolog A,hAPG4A,ATG4A,APG4A,AUTL2, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Human Autophagy Related 4 Homolog A is produced by our E.coli expression system and the target gene encoding Met1-Val398 is expressed with a 6His tag at the N-terminus.Accession:Q8WYN0. Expression Host:E.coli.Species:Human.Predicted Molecular Mass:47.5 KDa. Background:Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.